Archive for Cancer

Clay Siegall leads way in fight against cancer

Clay Siegall has spent his life dedicated to the research and development of novel cancer treatments. He first became aware of the barbarity of many forms of cancer treatments while he was in college. He decided to focus his career on the search for new, less invasive and less damaging ways to treat, and maybe someday cure the disease.



Combining old and new


After spending 15 years as a leading cancer researcher at Bristol-Meyers-Squibb and the National Cancer Institute, Dr. Siegall founded Seattle Genetics in 1998. The company’s mission was to concentrate on researching and developing a new line of promising anti-cancer drugs called antibody drug conjugates. These are a form of the broader category of drugs known as targeted cancer therapies.


These targeted therapies were developed in response to the often times horrific means by which cancer is treated. Prior to the 2000s, the two main treatment modalities for cancer were killing the cancer cells through such means as radiation and chemotherapy or excision of the tumor. This last option often involves radical surgery, including amputation of limbs and other body parts. Chemotherapy and radiation can be just as nasty, with recipients often having lifelong deficits, such as paresthesia or cardiomyopathy, and visibly accelerated aging, among many other terrible side-effects.


Siegall thought that there was a better way. While most targeted therapies, up until 2000 or so, had involved cytostatic agents, that is, agents which stop further proliferation of cancer cells, Siegall thought that the delivery mechanisms used in targeted therapies could be used to deliver much more potent cytotoxic agents, chemicals which actively kill tumor cells, sending the cancer into remission.


Between 1998 and 2011, Seattle Genetics developed a number of innovative approaches to developing the delivery systems that would take the cytotoxic chemicals directly to the site of the tumor without any systemic release, completely eliminating all of the traditional side-effects of chemotherapy while enhancing anti-cancer effects.


This culminated, in 2011, with the first FDA approval of a viable antibody drug conjugate, Seattle Genetics’ Adcetris. Today, Adcetris and similar drugs are revolutionizing the ways in which cancer is treated across the globe.

An 18-Year-Old Student Discovers Possible Cure for Cancer in Chia Seeds

There have been a lot of expectations put on the new generation of young people who are getting ready to enter the workforce. The world is in crisis, and we need the best and the brightest minds to lead us through this time of trouble, and Oliver Cloutier is going to be one of them. In fact, he already is.

Cloutier is only 18-years-old but has already accomplished more than most by studying chia seeds of all things. The young student had heard about supposed health and nutritional benefits the small seeds provided, so he decided to further investigate the ancient claims.

He extensively studied the history of chia seeds and how it was used in certain practices, some of which dated back thousands of years. And it turns out the ancients knew what hey were talking about. Cloutier found something he never expected when discovering chia seeds contained a molecule which could prove extremely effective at treating cancer.

Specific extracts from chia seeds have special cancer-fighting capabilities by inhibiting cells responsible for creating the disease according to Marcio Alaor BMG. The up-and-coming researcher is busy finding applications to his findings by developing a treatment using the amazing extracts found during his experiments with chia seeds.

The research also landed Cloutier a full college scholarship and first place in the Hydro-Quebec Science Expo last month.